| Estimation of urinary stone composition by automated processing of CT images. | |
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MedLine Citation:
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PMID: 19711066 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objective of this article was developing an automated tool for routine clinical practice to estimate urinary stone composition from CT images based on the density of all constituent voxels. A total of 118 stones for which the composition had been determined by infrared spectroscopy were placed in a helical CT scanner. A standard acquisition, low-dose and high-dose acquisitions were performed. All voxels constituting each stone were automatically selected. A dissimilarity index evaluating variations of density around each voxel was created in order to minimize partial volume effects: stone composition was established on the basis of voxel density of homogeneous zones. Stone composition was determined in 52% of cases. Sensitivities for each compound were: uric acid: 65%, struvite: 19%, cystine: 78%, carbapatite: 33.5%, calcium oxalate dihydrate: 57%, calcium oxalate monohydrate: 66.5%, brushite: 75%. Low-dose acquisition did not lower the performances (P < 0.05). This entirely automated approach eliminates manual intervention on the images by the radiologist while providing identical performances including for low-dose protocols. |
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Authors:
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Gr??goire Chevreau; Jocelyne Troccaz; Pierre Conort; Rapha??lle Renard-Penna; Alain Mallet; Michel Daudon; Pierre Mozer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-08-27 |
Journal Detail:
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Title: Urological research Volume: 37 ISSN: 1434-0879 ISO Abbreviation: Urol. Res. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-09-16 Completed Date: 2009-12-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0364311 Medline TA: Urol Res Country: Germany |
Other Details:
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Languages: eng Pagination: 241-5 Citation Subset: IM |
Affiliation:
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Department of Urology, Piti??-Salp??tri??re Hospital, Paris, France. Gregoire.Chevreau@imag.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calcium Oxalate
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analysis Calcium Phosphates / analysis Cystine / analysis Humans Sensitivity and Specificity Tomography, Spiral Computed / methods* Uric Acid / analysis Urinary Calculi / chemistry*, radiography* |
| Chemical | |
Reg. No./Substance:
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0/Calcium Phosphates; 14567-92-1/brushite; 25454-23-3/Calcium Oxalate; 56-89-3/Cystine; 69-93-2/Uric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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