Document Detail

Estimation of the stent placement above the intact sphincter of Oddi against malignant bile duct obstruction.
MedLine Citation:
PMID:  15830289     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In endoscopic biliary stenting against malignant biliary obstruction, stent blockage remains as an important problem. Stent blockage occurs as a result of bacterial adherence to the inner wall of the stent. We evaluated the stent placement above the intact sphincter of Oddi to retain the function of the sphincter of Oddi as a bacteriological barrier. METHODS: Sixteen patients with malignant biliary obstruction were assessed as the patients with the stent above the intact sphincter of Oddi. Sixteen patients with malignant biliary obstruction were assessed as the patients with the conventional stent placement across the sphincter of Oddi. Tannenbaum 10-Fr. stents were used in both the groups. RESULTS: The median patency periods of the stent were 255 days (25th to 75th percentiles, 212-454 days; range, 39-454 days) for the group of the stents placed above the sphincter of Oddi and 82 days (25th to 75th percentiles, 48-131 days; range, 22-196 days) for the group of the stents placed across the sphincter of Oddi, respectively, with significant difference (P = 0.0001). The occlusion rates of stents placed above and across the sphincter of Oddi were 37.5% and 93.8%, respectively, with significant difference (P = 0.0008). The dislocation rates of the stent were 0% and 6.3%, respectively (not significant). CONCLUSIONS: Placement of the stent above the intact sphincter of Oddi was associated with longer stent patency and lower occlusion rate.
Naohito Uchida; Kunihiko Tsutsui; Toru Ezaki; Hiroki Fukuma; Hideki Kamata; Hideki Kobara; Hiroshi Matsuoka; Fumihiko Kinekawa; Yuichi Aritomo; Fumi Yokoyama; Yuko Kita; Tsutomu Masaki; Mutsumi Ogawa; Toshiaki Nakatsu; Seishiro Watanabe; Shigeki Kuriyama
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of gastroenterology     Volume:  40     ISSN:  0944-1174     ISO Abbreviation:  J. Gastroenterol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-04-14     Completed Date:  2005-08-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9430794     Medline TA:  J Gastroenterol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  291-6     Citation Subset:  IM    
Third Department of Internal Medicine, Kagawa University School of Medicine, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
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MeSH Terms
Aged, 80 and over
Bile Duct Neoplasms / complications
Cholangiopancreatography, Endoscopic Retrograde
Cholestasis / etiology,  radiography,  surgery*
Endoscopy, Digestive System
Follow-Up Studies
Gallbladder Neoplasms / complications
Pancreatic Neoplasms / complications
Prosthesis Failure
Prosthesis Implantation / instrumentation*,  methods
Retrospective Studies
Sphincter of Oddi
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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