Document Detail

Estimation of skeletal muscle mass by bioelectrical impedance analysis.
MedLine Citation:
PMID:  10926627     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to develop and cross-validate predictive equations for estimating skeletal muscle (SM) mass using bioelectrical impedance analysis (BIA). Whole body SM mass, determined by magnetic resonance imaging, was compared with BIA measurements in a multiethnic sample of 388 men and women, aged 18-86 yr, at two different laboratories. Within each laboratory, equations for predicting SM mass from BIA measurements were derived using the data of the Caucasian subjects. These equations were then applied to the Caucasian subjects from the other laboratory to cross-validate the BIA method. Because the equations cross-validated (i.e., were not different), the data from both laboratories were pooled to generate the final regression equation SM mass (kg) = [(Ht<SUP>2</SUP>/ <IT>R</IT> x 0.401) + (gender x 3.825) + (age x -0. 071)] + 5.102 where Ht is height in centimeters; R is BIA resistance in ohms; for gender, men = 1 and women = 0; and age is in years. The r(2) and SE of estimate of the regression equation were 0.86 and 2.7 kg (9%), respectively. The Caucasian-derived equation was applicable to Hispanics and African-Americans, but it underestimated SM mass in Asians. These results suggest that the BIA equation provides valid estimates of SM mass in healthy adults varying in age and adiposity.
I Janssen; S B Heymsfield; R N Baumgartner; R Ross
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  89     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-09-15     Completed Date:  2000-09-15     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  465-71     Citation Subset:  IM; S    
School of Physical and Health Education, Queen's University, Kingston, Ontario, Canada.
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MeSH Terms
Aged, 80 and over
Body Weight / physiology
Continental Population Groups
Electric Impedance / diagnostic use*
Magnetic Resonance Imaging
Middle Aged
Models, Biological
Muscle, Skeletal / anatomy & histology*
Regression Analysis
Reproducibility of Results
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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