Document Detail


Estimation of risks of pesticide exposure, by food intake, to Koreans.
MedLine Citation:
PMID:  12842175     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to evaluate theoretical maximum daily intake (TMDI) and estimated daily intake (EDI) for Korean by using maximum residue levels (MRLs), food intake, residue data and correction factors, and compare with acceptable daily intake (ADI) in order to estimate the health risk based on the pesticide exposure. Then, the oncogenic risks of the pesticides were assessed from TMDI and estimated daily intake with treatment (adjusted EDI). The percent ratio of TMDI to ADI for 262 pesticides was mostly below 80%, but 42 pesticides (16.0%) exceeded the ADI. EDI without treatment (non-adjusted EDI) and estimated daily intake with treatment (adjusted EDI) were summed up to about 6.41 ml/day/capita and 2.94 ml/day/capita, respectively. The percentage of ADI was TMDI (101.04%) > non-adjusted EDI (0.08%) > adjusted EDI (0.01%), and the exposure level of Korean population to whole pesticides was below the level to produce health risk. The dietary oncogenic risk for Koreans was estimated to be 7.3x10(-4) on the basis of TMDI, 1.8x10(-7) on the basis of adjusted EDI, and although the level from TMDI exceeded the risk level (1x10(-6)) of the Environment Protection Agency (EPA), the level from adjusted EDI, real exposure level, was below it.
Authors:
Ock Kyoung Chun; Hee Gon Kang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  41     ISSN:  0278-6915     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-07-04     Completed Date:  2003-08-12     Revised Date:  2006-03-13    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1063-76     Citation Subset:  IM    
Affiliation:
Garak Agricultural Products Inspection Team, Seoul Health and Environmental Research Institute, Garak dong 600, Songpa ku, 138-701, Seoul, South Korea. oc28@cornell.edu
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MeSH Terms
Descriptor/Qualifier:
Eating
Environmental Exposure*
Environmental Monitoring
Food Analysis*
Food Contamination / analysis*
Food Supply*
Humans
Korea
Maximum Allowable Concentration
Pesticide Residues / adverse effects,  analysis*
Risk Assessment
Chemical
Reg. No./Substance:
0/Pesticide Residues

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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