Document Detail


Estimation of the quasi-static Young's modulus of the eardrum using a pressurization technique.
MedLine Citation:
PMID:  23270964     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The quasi-static Young's modulus of the eardrum's pars tensa is an important modeling parameter in computer simulations. Recent developments in indentation testing and inverse modeling allow estimation of this parameter with the eardrum in situ. These approaches are challenging because of the curved shape of the pars tensa which requires special care during experimentation to keep the indenter perpendicular to the local surface at the point of contact. Moreover, they involve complicated contact modeling. An alternative computer-based method is presented here in which pressurization is used instead of indentation. The Young's modulus of a thin-shell model of the eardrum with subject-specific geometry is numerically optimized such that simulated pressurized shapes match measured counterparts. The technique was evaluated on six healthy rat eardrums, resulting in a Young's modulus estimate of 22.8±1.5MPa. This is comparable to values estimated using indentation testing. The new pressurization-based approach is simpler to use than the indentation-based method for the two reasons noted above.
Authors:
Nastaran Ghadarghadar; Sumit K Agrawal; Abbas Samani; Hanif M Ladak
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-24
Journal Detail:
Title:  Computer methods and programs in biomedicine     Volume:  -     ISSN:  1872-7565     ISO Abbreviation:  Comput Methods Programs Biomed     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506513     Medline TA:  Comput Methods Programs Biomed     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Electrical and Computer Engineering, Western University, London, Ontario, Canada.
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