| Estimation of pulmonary artery pressure in patients with primary pulmonary hypertension by quantitative analysis of magnetic resonance images. | |
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MedLine Citation:
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PMID: 8083939 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The use of magnetic resonance (MR) images for estimating mean pulmonary artery pressure (PAP) was tested by comparing main pulmonary artery (MPA) and middescending thoracic aorta (AO) caliber in 12 patients with primary pulmonary hypertension (PPH) with measurements made in eight other patients who were observed for diseases other than heart disease (controls). The ratio MPA/AO and the ratios of vessel caliber normalized to body surface area (MPAI and AOI, respectively) were computed. The PAP was obtained in all PPH patients and compared with caliber measurements. The PPH MPA (3.6 +/- 0.8 cm) was significantly larger than the control MPA (2.9 +/- 0.3 cm, p = 0.02); the PPH MPAI (2.8 +/- 0.7 cm/M2) was significantly greater than the control MPA (1.7 +/- 0.2 cm/M2, p < 0.0001). Control AO (2.2 +/- 0.3 cm) was significantly greater than PPH AO (1.6 +/- 0.4 cm, p < 0.0001); there was no significant difference between control AOI (1.3 +/- 0.2 cm/M2) and PPH AOI (1.2 +/- 0.2 cm/M2, p = 0.25). The PPH MPA/AO (2.3 +/- 0.6) was significantly greater than the control MPA/AO (1.3 +/- 0.1, p < 0.0001); overlap between MPA in the two groups was eliminated by indexing values to AO caliber (MPA/AO). Among PPH patients there was strong correlation between PAP and MPA/AO (PAP = 24 x MPA/AO + 3.7, r = 0.7, p < 0.01). Increased MPA/AO denotes the presence of pulmonary hypertension and may be used to estimate PAP. |
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Authors:
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T I Murray; L M Boxt; J Katz; K Reagan; R J Barst |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of thoracic imaging Volume: 9 ISSN: 0883-5993 ISO Abbreviation: J Thorac Imaging Publication Date: 1994 |
Date Detail:
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Created Date: 1994-10-11 Completed Date: 1994-10-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8606160 Medline TA: J Thorac Imaging Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 198-204 Citation Subset: IM |
Affiliation:
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Department of Radiology, College of Physicians and Surgeons of Columbia University, New York, New York. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angiography Aorta, Thoracic / pathology, physiopathology Blood Pressure / physiology* Body Surface Area Child Child, Preschool Female Humans Hypertension, Pulmonary / diagnosis*, pathology, radiography Image Processing, Computer-Assisted Infant Magnetic Resonance Imaging* / methods Male Middle Aged Pulmonary Artery / pathology*, physiopathology, radiography Pulmonary Wedge Pressure / physiology Retrospective Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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