| Estimation of maximum ventricular elastance under assistance with a rotary blood pump. | |
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MedLine Citation:
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PMID: 20633160 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The maximum ventricular elastance is a reliable index for assessing the cardiac function from changes in its pressure-volume relationship. The advantage of this index is that it can represent the contractility of either unassisted hearts or native hearts assisted with rotary blood pumps. However, there are situations in which changes in the ventricular load required for the conventional estimation method might be risky. For example, in a bridge-to-recovery the cardiac function should also be continuously observed after the implantation of a rotary blood pump. In this article, we present the results of the estimation of the maximum elastance with in vivo data using the parameter optimization method, which is a single-beat estimation method. The estimated values for the normal cardiac function (6.8 +/- 0.6, 4.5 +/- 0.9, 4.2 +/- 1.8 mm Hg/mL) were significantly different from those for the low cardiac function (3.2 +/- 1.5, 1.9 +/- 1.0, 1.9 +/- 1.2 mm Hg/mL) from the data of the three animals that were analyzed. Besides, the maximum elastance values were independent of the pump rotational speed. These results indicate that this index might be useful for the detection of the myocardial recovery. |
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Authors:
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Telma K Sugai; Akira Tanaka; Makoto Yoshizawa; Yasuyuki Shiraishi; Tomoyuki Yambe; Shin-ichi Nitta; Atsushi Baba |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Artificial organs Volume: 34 ISSN: 1525-1594 ISO Abbreviation: Artif Organs Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-07-16 Completed Date: 2010-10-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802778 Medline TA: Artif Organs Country: United States |
Other Details:
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Languages: eng Pagination: 442-6 Citation Subset: IM |
Affiliation:
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Graduate School of Biomedical Engineering, Tohoku University, Yoshizawa Laboratory, 6-6-05 Aoba, Aramaki, Aoba-ku, Sendai, Japan. telma@yoshizawa.ecei.tohoku.ac.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Female Goats Heart-Assist Devices* Models, Cardiovascular Myocardial Contraction Ventricular Function* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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