Document Detail

Estimation of intraocular pressure in rabbits with commonly used tonometers.
MedLine Citation:
PMID:  17278535     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVES: To validate accuracy and reproducibility of the Perkins tonometer, pneumatonometer, and Tono-Pen XL (Medtronic Solan, Jacksonville, FL) in estimating intraocular pressure (IOP) in rabbits. MATERIALS AND METHODS: IOP was increased from 5 to 50 mm Hg in 5-mm increments. Measurements were compared to readings of two digital manometers simultaneously measuring real IOP in the anterior chamber and vitreous cavity. Interobserver accuracy was evaluated using 4 eyes with the Perkins tonometer. RESULTS: The Perkins tonometer and Tono-Pen XL underestimated IOP and were more accurate at pressures less than 30 mm Hg. No statistically significant difference was found between real IOP and Tono-Pen XL readings. The pneumatonometer overestimated pressures in the low ranges but was accurate at pressures greater than 40 mm Hg. The Tono-Pen XL had more variability than the Perkins tonometer and pneumatonometer at high IOP. CONCLUSIONS: None of the tonometers are accurate or reproducible in estimating IOP in rabbits over the tested range. Pneumatonometry, although not very accurate, has the advantage of having acceptable variability.
Ana C Acosta; Edgar M Espana; Izuru Nose; Marcia Orozco; Hideo Yamamoto; Anna S Venkatraman; Francisco Fantes; Jean-Marie Parel
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye     Volume:  38     ISSN:  1542-8877     ISO Abbreviation:  Ophthalmic Surg Lasers Imaging     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2007-02-06     Completed Date:  2007-02-27     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  101155780     Medline TA:  Ophthalmic Surg Lasers Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  43-9     Citation Subset:  IM    
Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, 1638 NW10th Avenue, Miami, FL 33136, USA.
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MeSH Terms
Cornea / anatomy & histology
Equipment Design
Intraocular Pressure / physiology*
Observer Variation
Reproducibility of Results
Tonometry, Ocular / instrumentation*
Grant Support

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