Document Detail

Estimation of inspiratory muscle pressure in critically ill patients.
MedLine Citation:
PMID:  20107765     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Recently, a new technology has been introduced aiming to monitor and improve patient ventilator interaction (PVI monitor). With the PVI monitor, a signal representing an estimation of the patient's total inspiratory muscle pressure (Pmus(PVI)) is calculated from the equation of motion, utilizing estimated values of resistance and elastance of the respiratory system.
OBJECTIVE: The aim of the study was to prospectively examine the accuracy of Pmus(PVI) to quantify inspiratory muscle pressure.
METHODS AND INTERVENTIONS: Eleven critically ill patients mechanically ventilated on proportional assist ventilation with load-adjustable gain factors were studied at three levels of assist (30, 50 and 70%). Airway, esophageal, gastric and transdiaphragmatic (Pdi) pressures, volume and flow were measured breath by breath, whereas the total inspiratory muscle pressure (Pmus) was calculated using the Campbell diagram.
RESULTS: For a given assist, Pmus(PVI) throughout inspiration did not differ from the corresponding values calculated using the Pdi and Pmus signals. Inspiratory and expiratory time did not differ among the various methods of calculation. Inspiratory muscle pressure decreased with increasing assist, and the magnitude of this decrease did not differ among the various methods of pressure calculation.
CONCLUSIONS: A signal generated from flow, volume and airway pressure may be used to provide breath-by-breath quantitative information of inspiratory muscle pressure.
Eumorfia Kondili; Christina Alexopoulou; Nectaria Xirouchaki; Katerina Vaporidi; Dimitris Georgopoulos
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Publication Detail:
Type:  Journal Article     Date:  2010-01-28
Journal Detail:
Title:  Intensive care medicine     Volume:  36     ISSN:  1432-1238     ISO Abbreviation:  Intensive Care Med     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-12     Completed Date:  2010-06-10     Revised Date:  2012-09-10    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  648-55     Citation Subset:  IM    
Intensive Care Medicine Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece.
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MeSH Terms
Analysis of Variance
Critical Illness*
Diaphragm / physiology
Esophagus / physiology
Middle Aged
Monitoring, Physiologic / instrumentation*
Prospective Studies
Pulmonary Ventilation / physiology
Respiration, Artificial / methods*
Respiratory Muscles / physiology*
Signal Processing, Computer-Assisted
Stomach / physiology
Thoracic Wall / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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