Document Detail

Estimation of infarct size using serum troponin T concentration in patients with acute myocardial infarction.
MedLine Citation:
PMID:  8230683     Owner:  NLM     Status:  MEDLINE    
To estimate the size of myocardial infarction, serum troponin T concentration was measured in 34 patients with acute myocardial infarction. Left ventriculography, 2-dimensional echocardiography and resting 201thallium myocardial single photon emission computed tomography (SPECT) were performed about 4 weeks after the onset of myocardial infarction and used for correlation with the late serum troponin T peak concentration which occurred on the 3rd to 5th day after onset. Both left ventricular ejection fraction (LVEF) obtained from left ventriculography and wall motion index (WMI) obtained from 2-dimensional echocardiography were inversely related to late troponin T peak value (LVEF: r = 0.68, p < 0.001, WMI: r = 0.70, p < 0.001). Extent score (ES) and severity score (SS), which were estimated from the initial resting 201thallium SPECT image, showed excellent linear correlations with late troponin T peak concentrations (ES: r = 0.77, p < 0.001, SS: r = 0.66, p < 0.001). This correlation was present both in patients with an early troponin T peak on day 1 (group A-16 patients) and in those without an early peak (group B-10 patients). Thus, late troponin T peak concentration can be used to predict infarct size regardless of the kinetics of its appearance in serum.
T Omura; M Teragaki; T Tani; H Yamagishi; S Yanagi; T Nishikimi; M Yoshiyama; I Toda; K Akioka; K Takeuchi
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  57     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1993-12-17     Completed Date:  1993-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1062-70     Citation Subset:  IM    
Department of Internal Medicine, Osaka City University Medical School, Japan.
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MeSH Terms
Heart / radionuclide imaging
Heart Ventricles / radiography
Middle Aged
Myocardial Infarction / blood,  diagnosis,  pathology*
Thallium Radioisotopes / diagnostic use
Tomography, Emission-Computed, Single-Photon
Troponin / blood*
Troponin T
Reg. No./Substance:
0/Thallium Radioisotopes; 0/Troponin; 0/Troponin T

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