Document Detail

Estimation of fast vagal response by time-dependent analysis of heart rate variability in normal subjects.
MedLine Citation:
PMID:  8985620     Owner:  NLM     Status:  MEDLINE    
In this study, the selective windowed discrete Fourier transform algorithm (SDA) for time-frequency analysis was applied on non-stationary heart rate signals, recorded during vagal perturbations. These perturbations were achieved in healthy subjects (aged 6-42 years) by inducing the oculocardiac reflex and the diving response. The results showed that the SDA can detect and quantify the expected, although brief, increase in vagal tone, by displaying a marked transient increase in the respiratory peak of the time-dependent spectrum. It allowed us to demonstrate an age-dependent reduction of the vagal response, obtained from the respiratory peak of the heart rate time-dependent spectrum. The SDA approach is thus an adequate tool for the evaluation of an instantaneous change in vagal activity, as well as steady-state vagal activity, including the detection of a malfunction or an exaggerated response of the parasympathetic tone. Since changes in heart rate control are expressed by a transient response, they would not have been detected by a standard, steady-state spectral analysis of heart rate variability, which requires the consideration of long and steady trace lengths and would therefore cause smearing of such fast changes. Time-dependent, or transient changes in autonomic control can thus be detected and quantified by SDA time-frequency analysis.
L Keselbrener; A Baharav; S Akselrod
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical autonomic research : official journal of the Clinical Autonomic Research Society     Volume:  6     ISSN:  0959-9851     ISO Abbreviation:  Clin. Auton. Res.     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-04-11     Completed Date:  1997-04-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9106549     Medline TA:  Clin Auton Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  321-7     Citation Subset:  IM    
Abramson Institute of Medical Physics, Sackler Faculty of Exact Sciences, Tel Aviv University, Israel.
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MeSH Terms
Cold Temperature*
Fourier Analysis
Heart Rate / physiology*
Reference Values
Reflex, Oculocardiac / physiology*
Time Factors
Trigeminal Nerve / physiology
Vagus Nerve / physiology*

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