Document Detail


Estimation and characterisation of budesonide tablets impurities.
MedLine Citation:
PMID:  18367362     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Budesonide is the 16alpha,17alpha-acetal of 16alpha-hydroxyprednisolone with n-butyraldehyde, endowed with anti-inflammatory activity. In a sample of budesonide tablets, kept for 3 years at 25 degrees C and 60% RH unknown impurities, not reported in European Pharmacopoiea, were present. Their identification was achieved by means of chemical and spectroscopic methods.
Authors:
Patrizia Ferraboschi; Vittorio Bertacche; Isabella Maccone; Elena Pini; Laura Ragonesi; Alessio Venturini; Riccardo Stradi
Publication Detail:
Type:  Journal Article     Date:  2008-02-16
Journal Detail:
Title:  Journal of pharmaceutical and biomedical analysis     Volume:  47     ISSN:  0731-7085     ISO Abbreviation:  J Pharm Biomed Anal     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-05-27     Completed Date:  2008-09-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309336     Medline TA:  J Pharm Biomed Anal     Country:  England    
Other Details:
Languages:  eng     Pagination:  636-40     Citation Subset:  IM    
Affiliation:
Dipartimento di Chimica, Biochimica e Biotecnologie per la Medicina, Università di Milano-Via Saldini, 50-20133 Milano, Italy. patrizia.ferraboschi@unimi.it
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MeSH Terms
Descriptor/Qualifier:
Budesonide / analysis*
Chromatography, High Pressure Liquid
Drug Contamination*
Tablets
Chemical
Reg. No./Substance:
0/Tablets; 51333-22-3/Budesonide

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