Document Detail

Estimation and characterisation of budesonide tablets impurities.
MedLine Citation:
PMID:  18367362     Owner:  NLM     Status:  MEDLINE    
Budesonide is the 16alpha,17alpha-acetal of 16alpha-hydroxyprednisolone with n-butyraldehyde, endowed with anti-inflammatory activity. In a sample of budesonide tablets, kept for 3 years at 25 degrees C and 60% RH unknown impurities, not reported in European Pharmacopoiea, were present. Their identification was achieved by means of chemical and spectroscopic methods.
Patrizia Ferraboschi; Vittorio Bertacche; Isabella Maccone; Elena Pini; Laura Ragonesi; Alessio Venturini; Riccardo Stradi
Publication Detail:
Type:  Journal Article     Date:  2008-02-16
Journal Detail:
Title:  Journal of pharmaceutical and biomedical analysis     Volume:  47     ISSN:  0731-7085     ISO Abbreviation:  J Pharm Biomed Anal     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-05-27     Completed Date:  2008-09-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309336     Medline TA:  J Pharm Biomed Anal     Country:  England    
Other Details:
Languages:  eng     Pagination:  636-40     Citation Subset:  IM    
Dipartimento di Chimica, Biochimica e Biotecnologie per la Medicina, Università di Milano-Via Saldini, 50-20133 Milano, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Budesonide / analysis*
Chromatography, High Pressure Liquid
Drug Contamination*
Reg. No./Substance:
0/Tablets; 51333-22-3/Budesonide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Hypoparathyroidism and intracerebral calcification in patients with beta-thalassemia major.
Next Document:  Effect of beta-cyclodextrin and hydroxypropyl beta-cyclodextrin complexation on physicochemical prop...