Document Detail

[Estimation of absolute risk for fracture].
MedLine Citation:
PMID:  19491514     Owner:  NLM     Status:  MEDLINE    
Osteoporosis treatment aims to prevent fractures and maintain the QOL of the elderly. However, persons at high risk of future fracture cannot be effectively identified on the basis of bone density (BMD) alone, although BMD is used as an diagnostic criterion. Therefore, the WHO recommended that absolute risk for fracture (10-year probability of fracture) for each individual be evaluated and used as an index for intervention threshold. The 10-year probability of fracture is calculated based on age, sex, BMD at the femoral neck (body mass index if BMD is not available), history of previous fractures, parental hip fracture history, smoking, steroid use, rheumatoid arthritis, secondary osteoporosis and alcohol consumption. The WHO has just announced the development of a calculation tool (FRAX: WHO Fracture Risk Assessment Tool) in February this year. Fractures could be prevented more effectively if, based on each country's medical circumstances, an absolute risk value for fracture to determine when to start medical treatment is established and persons at high risk of fracture are identified and treated accordingly.
Saeko Fujiwara
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Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics     Volume:  46     ISSN:  0300-9173     ISO Abbreviation:  Nihon Ronen Igakkai Zasshi     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-06-03     Completed Date:  2009-09-21     Revised Date:  2011-07-29    
Medline Journal Info:
Nlm Unique ID:  7507332     Medline TA:  Nihon Ronen Igakkai Zasshi     Country:  Japan    
Other Details:
Languages:  jpn     Pagination:  128-30     Citation Subset:  IM    
Department of Clinical Studies, Radiation Effects Research Foundation.
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MeSH Terms
Bone Density
Fractures, Bone* / prevention & control

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