Document Detail


Estimating the spontaneous loss of Down syndrome fetuses between the times of chorionic villus sampling, amniocentesis and livebirth.
MedLine Citation:
PMID:  9826896     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent publications concerning the prevalence of Down syndrome at times of chorionic villus sampling (CVS), amniocentesis and livebirth were reviewed with particular interest in estimates of spontaneous loss of Down syndrome fetuses during pregnancy. Data from several studies were combined to provide information on 258,206 pregnancies. A logistic regression was applied to provide new estimates and confidence intervals (CIs) for spontaneous loss rates between the time of CVS and livebirth (estimate = 39 per cent; 90 per cent CI 32 to 45 per cent), and the time of amniocentesis and livebirth (estimate = 12 per cent; 90 per cent CI 5 to 18 per cent).
Authors:
I C Bray; D E Wright
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  18     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-01-28     Completed Date:  1999-01-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1045-54     Citation Subset:  IM    
Affiliation:
School of Mathematics and Statistics, University of Plymouth, U.K.
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous*
Adult
Amniocentesis*
Chorionic Villi Sampling*
Down Syndrome* / diagnosis
Female
Gestational Age
Humans
Logistic Models
Pregnancy
Comments/Corrections
Comment In:
Prenat Diagn. 1999 Dec;19(12):1177-9   [PMID:  10590442 ]
Prenat Diagn. 2000 Aug;20(8):685-6   [PMID:  10951486 ]
Prenat Diagn. 2001 Sep;21(9):788-9   [PMID:  11559916 ]

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