Document Detail


Estimating the personal cure rate of cancer patients using population-based grouped cancer survival data.
MedLine Citation:
PMID:  20181780     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cancer patients are subject to multiple competing risks of death and may die from causes other than the cancer diagnosed. The probability of not dying from the cancer diagnosed, which is one of the patients' main concerns, is sometimes called the 'personal cure' rate. Two approaches of modelling competing-risk survival data, namely the cause-specific hazards approach and the mixture model approach, have been used to model competing-risk survival data. In this article, we first show the connection and differences between crude cause-specific survival in the presence of other causes and net survival in the absence of other causes. The mixture survival model is extended to population-based grouped survival data to estimate the personal cure rate. Using the colorectal cancer survival data from the Surveillance, Epidemiology and End Results Programme, we estimate the probabilities of dying from colorectal cancer, heart disease, and other causes by age at diagnosis, race and American Joint Committee on Cancer stage.
Authors:
Binbing Yu; Ram C Tiwari; Eric J Feuer
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural     Date:  2010-02-24
Journal Detail:
Title:  Statistical methods in medical research     Volume:  20     ISSN:  1477-0334     ISO Abbreviation:  Stat Methods Med Res     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-25     Completed Date:  2011-09-27     Revised Date:  2012-03-08    
Medline Journal Info:
Nlm Unique ID:  9212457     Medline TA:  Stat Methods Med Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  261-74     Citation Subset:  IM    
Affiliation:
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD 20892, USA. yubi@mail.nih.gov
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Cause of Death
Colorectal Neoplasms / mortality
Data Interpretation, Statistical
Female
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Models, Statistical
Neoplasms / mortality*,  therapy*
Proportional Hazards Models
Registries
Risk Factors
SEER Program / statistics & numerical data
Survival Analysis*
United States / epidemiology
Grant Support
ID/Acronym/Agency:
Z99 AG999999/AG/NIA NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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