Document Detail

Estimating errors and confidence intervals for branch lengths in phylogenetic trees by a bootstrap approach.
MedLine Citation:
PMID:  8006997     Owner:  NLM     Status:  MEDLINE    
A method, based on the bootstrap procedure, is proposed for the estimation of branch-length errors and confidence intervals in a phylogenetic tree for which equal rates of substitution among lineages do not necessarily hold. The method can be used to test whether an estimated internodal distance is significantly greater than zero. In the application of the method, any estimator of genetic distances, as well as any tree reconstruction procedure (based on distance matrices), can be used. Also the method is not limited by the number of species involved in the phylogenetic tree. An example of the application of the method in the reconstruction of the phylogenetic tree for the four hominoid species--human, chimpanzee, gorilla, and orangutan--is shown.
J Dopazo
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of molecular evolution     Volume:  38     ISSN:  0022-2844     ISO Abbreviation:  J. Mol. Evol.     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-07-18     Completed Date:  1994-07-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0360051     Medline TA:  J Mol Evol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  300-4     Citation Subset:  IM    
Centro de Investigacioń en Sanidad Animal, INIA, Madrid, Spain.
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MeSH Terms
Confidence Intervals
DNA, Mitochondrial / genetics
Evaluation Studies as Topic
Genetic Techniques*
Gorilla gorilla
Hominidae / classification,  genetics
Pan troglodytes
Pongo pygmaeus
Reg. No./Substance:
0/DNA, Mitochondrial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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