Document Detail


Estimating the cost-effectiveness of quality-improving interventions in oral anticoagulation management within general practice.
MedLine Citation:
PMID:  17076867     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: A clinical trial, "Belgian Improvement Study on Oral Anticoagulation Therapy (BISOAT)," significantly improved the quality after implementing four different quality-improving interventions in four randomly divided groups of general practitioners (GPs). The quality-improving interventions consisted of multifaceted education with or without feedback reports on their performance, international normalized ratio (INR) testing by the GP with a CoaguChek device or computer-assisted advice for adapting oral anticoagulation therapy. The quality improvement in INR control versus baseline was similar in the four groups. The aim of the current study was to calculate the cost-effectiveness and influencing factors of the four quality-improving interventions compared with usual care. METHODS: Activity-based costing techniques with questionnaires were used to determine the global costs per patient per month in the different intervention groups. Effectiveness data were obtained from the BISOAT study. Cost-effectiveness was expressed as cost per additional day within a 0.5 range from INR target. RESULTS: The one-time cost of multifaceted education was 49,997 euro for the whole study. Monthly continuous costs per intervention ranged between 37 euro and 54 euro per patient. Using the CoaguChek in combination with the multifaceted education was associated with net savings and quality improvement, hence dominated usual care. Sensitivity analyses showed improved cost-effectiveness with extended duration and with increased program size. CONCLUSION: Implementation of the combination multifaceted education with the use of the CoaguChek is a cost-effective new organizational model of oral anticoagulation management in general practice.
Authors:
Neree Claes; Karen Moeremans; Buntinx Frank; Arnout Jef; Vermylen Jos; Van Loon Herman; Annemans Lieven
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research     Volume:  9     ISSN:  1098-3015     ISO Abbreviation:  Value Health     Publication Date:    2006 Nov-Dec
Date Detail:
Created Date:  2006-11-01     Completed Date:  2007-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883818     Medline TA:  Value Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  369-76     Citation Subset:  IM    
Affiliation:
Department of General Practice, Catholic University Leuven, Leuven, Belgium. neree.claes@med.kuleuven.ac.be
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Anticoagulants / economics,  pharmacology*
Belgium
Clinical Competence
Cost-Benefit Analysis
Diagnosis, Computer-Assisted / economics
Drug Therapy, Computer-Assisted / economics
Education, Medical, Continuing / economics
Family Practice / economics*,  education,  standards*
Health Care Costs
Humans
International Normalized Ratio / economics,  utilization
Program Evaluation
Questionnaires
Specimen Handling / economics,  methods
Task Performance and Analysis
Total Quality Management / economics*,  methods*
Chemical
Reg. No./Substance:
0/Anticoagulants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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