Document Detail

Estimating chemical biotransformation rates from food web concentrations.
MedLine Citation:
PMID:  22248809     Owner:  NLM     Status:  Publisher    
Biotransformation is widely recognized as the most important and most uncertain determinant of bioaccumulation. A step-wise method for estimating organism-specific biotransformation half-lives from field observations and using established food web modeling is developed. As a proof of concept, the method is applied to the case of nine polycyclic aromatic hydrocarbons (PAHs) in a well-studied food web in Bohai Bay, China. The estimated half-lives are in good agreement with the existing literature. The proposed biotransformation estimation method, through data mining, for sufficiently defined ecosystems, may greatly reduce the necessary animal testing involved in chemical assessments by providing useful guidance to experimentalists and regulators.
Eva M Webster; David A Ellis
Related Documents :
25161039 - Large-scale single step partial purification of potato pectin methylesterase that enabl...
25162609 - How food controls aggression in drosophila.
22624439 - Lessons from cases of mortality due to food allergy in israel: cow's milk protein shoul...
22818719 - Translational research to reduce trans-fat intakes in northern québec (nunavik) inuit ...
22644579 - Flexibility and persistence of chimpanzee (pan troglodytes) foraging behavior in a capt...
22771079 - Understanding the process of establishing a food and nutrition policy: the case of slov...
8209229 - Simultaneous multielemental analysis of daily food samples by inductively coupled plasm...
15538709 - Bacillus cereus, the causative agent of an emetic type of food-borne illness.
7261399 - Accurate measurement of stable isotopes 46ca and 48ca in human feces, plasma, and urine...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-14
Journal Detail:
Title:  Chemosphere     Volume:  -     ISSN:  1879-1298     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0320657     Medline TA:  Chemosphere     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Centre for Environmental Modelling and Chemistry, Trent University, 1600 West Bank Drive, Peterborough, Ontario, Canada K9J 7B8.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of three methods to identify the anaerobic threshold during maximal exercise testing in p...
Next Document:  Modelling the role of size, edge structure and terminations on the electronic properties of trigonal...