Document Detail

Estimates, power and sample size calculations for two-sample ordinal outcomes under before-after study designs.
MedLine Citation:
PMID:  12754716     Owner:  NLM     Status:  MEDLINE    
Sample size calculations are given for comparing two groups of subjects, typically referring to active and non-active intervention groups, on an ordinal outcome in experiments where the subjects are measured before and after intervention. These calculations apply to log-odds models with random intercepts, treatment, time and treatment-by-time interaction terms, the latter being the term of interest. The assumed forms of the odds ratios are flexible, allowing for proportional odds, adjacent categories, or other conditional models for ordinal responses. Simulations studies show that, for given sample sizes, the nominal and actual powers of the proposed test are similar.
Pamela A Ohman Strickland; Shou-En Lu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Statistics in medicine     Volume:  22     ISSN:  0277-6715     ISO Abbreviation:  Stat Med     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-05-19     Completed Date:  2003-09-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8215016     Medline TA:  Stat Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1807-18     Citation Subset:  IM    
Copyright Information:
Copyright 2003 John Wiley & Sons, Ltd.
Division of Biometrics, School of Public Health and Cancer Institute of New Jersey, University of Medicine of Dentistry of New Jersey, Suite 2200, Liberty Plaza, 335 George Street, New Brunswick, NJ 08903, USA.
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MeSH Terms
Clinical Trials as Topic / methods,  statistics & numerical data*
Data Interpretation, Statistical*
Odds Ratio
Sample Size*
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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