Document Detail


Estimated glomerular filtration rate evolution between 6 and 24 months predicts long-term kidney transplant survival among patients with inferior graft function.
MedLine Citation:
PMID:  19857668     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
RESULTS: Among the groups, the eGFR improved among 47% of patients. Demographic characteristics including time on dialysis, human leukocyte antigen matching, cold ischemia times were similar across groups. A greater incidence of disadvantageous characteristics was observed among the deteriorating groups: older donor, higher delayed graft function incidence, as well as more frequent and severe acute rejection episodes. Excellent and comparable 5-year graft survivals were noticed among patients with improved eGFR between 6 and 24 months (97%, 100%, 100%, 94%).
CONCLUSION: Assessment of eGFR was a valuable biomarker for long-term kidney transplant outcomes among patients with inferior renal transplant function. A tendency to improve eGFR between 6 and 24 months posttransplant was advantageous for graft survival, possibly indicating state of immunologic quiescence.
Authors:
M Magott-Procelewska; M Boratynska; D Janczak; P Chudoba; D Patrzałek; P Biecek; M Klinger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplantation proceedings     Volume:  41     ISSN:  1873-2623     ISO Abbreviation:  Transplant. Proc.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-27     Completed Date:  2010-03-01     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0243532     Medline TA:  Transplant Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3028-32     Citation Subset:  IM    
Affiliation:
Department of Nephrology and Transplantation Medicine, Wroclaw Technical University, Traugutta street 57, 50-417 Wroclaw, Poland. marimagott@wp.pl
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Follow-Up Studies
Food Habits
Glomerular Filtration Rate / physiology*
Graft Survival / physiology
HLA Antigens / immunology
Histocompatibility Testing
Humans
Kidney Transplantation / immunology,  pathology,  physiology*
Male
Predictive Value of Tests
Time Factors
Tissue Donors
Transplantation, Homologous
Treatment Failure
Treatment Outcome
Chemical
Reg. No./Substance:
0/HLA Antigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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