Document Detail


Establishment and preliminary characterization of a cell line persistently infected with Newcastle disease virus.
MedLine Citation:
PMID:  6324529     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A murine osteosarcoma (OGS) cell line was permanently infected with Newcastle disease virus (NDV). The presence of NDV in the subsequent passages was demonstrated by haemadsorption and by immunofluorescence. Compared to the uninfected OGS line the persistently infected cells had a slightly reduced growth rate and they had a reduced sensitivity to several viruses, shown by several different methods. Interferon sensitivity was considerably reduced in the OGS-NDV cells, both the antiviral activity and the cell multiplication inhibitory activity.
Authors:
M Degré; L A Glasgow
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology     Volume:  91     ISSN:  0108-0180     ISO Abbreviation:  Acta Pathol Microbiol Immunol Scand B     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-05-21     Completed Date:  1984-05-21     Revised Date:  2009-06-04    
Medline Journal Info:
Nlm Unique ID:  8206623     Medline TA:  Acta Pathol Microbiol Immunol Scand B     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  389-94     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Division*
Cell Line
Interferon Type I / pharmacology*
Mice
Newcastle disease virus / physiology*
Osteosarcoma
Vesicular stomatitis Indiana virus / growth & development
Viruses / growth & development
Chemical
Reg. No./Substance:
0/Interferon Type I

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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