| Establishment of epithelial cell strains from normal adult mouse lung resembling a urethane-induced lung adenoma cell strain and a metastasizing mouse lung carcinoma cell line. | |
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MedLine Citation:
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PMID: 6713549 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Epithelial cell strains, designated NAL, have been established from normal lungs of adult female Balb/c mice. The ultrastructural characteristics, effect of dexamethasone on cellular morphology and proliferation rate, and the cytoskeletal protein pattern of NAL suggests that these cell strains may be related to a urethane-induced mouse lung adenoma cell strain NUL and to a metastasizing mouse lung tumour cell line CMT. NAL exhibited no anchorage-independent growth under normal conditions, however extensive passaging in the presence of 5 X 10(-6)M dexamethasone resulted in a colony forming efficiency in soft agar of 8.4% at passage number 30. |
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Authors:
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G J Smith; S M Le Mesurier; M L de Montfort; A W Lykke |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cell biology international reports Volume: 8 ISSN: 0309-1651 ISO Abbreviation: Cell Biol. Int. Rep. Publication Date: 1984 Feb |
Date Detail:
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Created Date: 1984-06-19 Completed Date: 1984-06-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7708050 Medline TA: Cell Biol Int Rep Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 161-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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pathology* Animals Carcinoma / pathology* Cell Division / drug effects Cell Line Dexamethasone / pharmacology Female Lung / cytology* Lung Neoplasms / pathology* Mice Neoplasm Metastasis Neoplasm Proteins / analysis Urethane |
| Chemical | |
Reg. No./Substance:
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0/Neoplasm Proteins; 50-02-2/Dexamethasone; 51-79-6/Urethane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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