Document Detail

Establishing and maintaining gene expression patterns: insights from sensory receptor patterning.
MedLine Citation:
PMID:  23293281     Owner:  NLM     Status:  MEDLINE    
In visual and olfactory sensory systems with high discriminatory power, each sensory neuron typically expresses one, or very few, sensory receptor genes, excluding all others. Recent studies have provided insights into the mechanisms that generate and maintain sensory receptor expression patterns. Here, we review how this is achieved in the fly retina and compare it with the mechanisms controlling sensory receptor expression patterns in the mouse retina and in the mouse and fly olfactory systems.
Jens Rister; Claude Desplan; Daniel Vasiliauskas
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Development (Cambridge, England)     Volume:  140     ISSN:  1477-9129     ISO Abbreviation:  Development     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-07     Completed Date:  2013-03-07     Revised Date:  2014-02-04    
Medline Journal Info:
Nlm Unique ID:  8701744     Medline TA:  Development     Country:  England    
Other Details:
Languages:  eng     Pagination:  493-503     Citation Subset:  IM    
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MeSH Terms
Cell Differentiation
Compound Eye, Arthropod / cytology,  metabolism
Drosophila / cytology*,  genetics,  metabolism
Drosophila Proteins / genetics,  metabolism
Gene Expression Regulation*
Olfactory Mucosa / cytology,  metabolism
Photoreceptor Cells, Vertebrate / cytology,  metabolism
Retina / cytology*,  metabolism
Rhodopsin / genetics,  metabolism
Rod Opsins / genetics,  metabolism*
Sensory Receptor Cells / cytology*,  metabolism
Transcription, Genetic
Grant Support
Reg. No./Substance:
0/Drosophila Proteins; 0/Rh5 protein, Drosophila; 0/Rh6 protein, Drosophila; 0/Rod Opsins; 0/middle-wavelength opsin; 0/short-wavelength opsin; 9009-81-8/Rhodopsin

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