Document Detail


Establishing targets for hypertension control in patients with comorbidities.
MedLine Citation:
PMID:  20848323     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Most current guidelines recommend tighter blood pressure (BP) control in hypertensive patients with comorbidities. These recommendations are based on epidemiologic data indicating that cardiovascular risk increases at lower BP levels in hypertensive patients with comorbidities than in those without comorbidities. Hypertension guidelines usually reflect outcomes from previous studies, but current recommendations for patients with comorbidities have preceded the evidence. We review recent studies investigating whether these new targets can be achieved, whether they are well tolerated, and whether they positively affect the outcomes. The results of the few current studies about outcomes in lower BP target groups are either negative or somewhat--but not decidedly--positive. There is a need for new trials designed to evaluate the validity of current recommendations for tighter BP control in hypertensive patients with comorbidities. Additionally, existing data from published trials could be reanalyzed to provide further clarification.
Authors:
Carlos Feldstein; Stevo Julius
Related Documents :
2888953 - Are some hypertensive patients overtreated? a prospective study of ambulatory blood pre...
16446323 - Mechanisms of hypertension associated with bay 43-9006.
11459213 - Pharmacology and clinical efficacy of angiotensin receptor blockers.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current hypertension reports     Volume:  12     ISSN:  1534-3111     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  465-73     Citation Subset:  IM    
Affiliation:
Hypertension Program, Hospital de Clinicas J. de San Martin, University of Buenos Aires School of Medicine, Buenos Aires, Argentina.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Surgery for oesophageal cancer at Galway University Hospital 1993-2008.
Next Document:  Management of patent foramen ovale and stroke.