Document Detail

Essential role of fats throughout the lifecycle. Background: the renaissance of fat: roles in membrane structure, signal transduction and gene expression.
MedLine Citation:
PMID:  12064968     Owner:  NLM     Status:  MEDLINE    
The intracellular and intramembrane profiles of fatty acids mirror those of dietary fat intake. The properties of transporter and receptor proteins embedded within cell membranes are influenced by the composition of the phospholipid membrane of cells. Many cell-signalling pathways involve lipids or lipid-derived molecules. Specific fatty acids are increasingly being identified as key regulators of gene expression and tissue differentiation.
Gareth S Denyer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Medical journal of Australia     Volume:  176 Suppl     ISSN:  0025-729X     ISO Abbreviation:  Med. J. Aust.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-14     Completed Date:  2005-09-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400714     Medline TA:  Med J Aust     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  S109-10     Citation Subset:  IM    
Department of Biochemistry, The University of Sydney, Sydney, NSW 2006, Australia.
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MeSH Terms
Cell Membrane / physiology*
Dietary Fats / pharmacology*
Fatty Acids / physiology*
Signal Transduction / physiology*
Reg. No./Substance:
0/Dietary Fats; 0/Fatty Acids

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