| Essential fatty acids and abnormal involuntary movements in the general male population: a study of men born in 1933. | |
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MedLine Citation:
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PMID: 8888128 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Spontaneous and tardive dyskinesias were studied in a random population sample of 446 men, aged 59 years. Dyskinesia, defined as an AIMS score of at least 2 in any body part, was seen in 15.1% (n = 74). Dyskinetic men had a higher cigarette consumption, and they had higher frequencies of psychiatric morbidity and exposure to neuroleptics. Dyskinesia was also associated with several abnormalities in EFA concentrations in plasma, but the most consistent finding was the low arachidonic acid levels in phospholipids, triglycerides and cholesterol esters. In a logistic regression model, cigarette consumption (P < 0.02), exposure to neuroleptics (P < 0.01), and low arachidonic acid levels in the phospholipid fraction (P < 0.0001) were independently associated with dyskinesia. |
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Authors:
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A Nilsson; D F Horrobin; A Rosengren; L Waller; A Adlerberth; L Wilhelmsen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Prostaglandins, leukotrienes, and essential fatty acids Volume: 55 ISSN: 0952-3278 ISO Abbreviation: Prostaglandins Leukot. Essent. Fatty Acids Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1997-02-13 Completed Date: 1997-02-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8802730 Medline TA: Prostaglandins Leukot Essent Fatty Acids Country: SCOTLAND |
Other Details:
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Languages: eng Pagination: 83-7 Citation Subset: IM |
Affiliation:
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Karsudden Hospital, Katrineholm, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antipsychotic Agents
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adverse effects Cohort Studies Fatty Acids / blood Fatty Acids, Essential / blood* Follow-Up Studies Humans Logistic Models Male Middle Aged Movement Disorders / blood, epidemiology*, physiopathology Odds Ratio Phospholipids / chemistry* Prevalence Prospective Studies Smoking / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 0/Fatty Acids; 0/Fatty Acids, Essential; 0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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