| The Essen Stroke Risk Score in One-Year Follow-Up Acute Ischemic Stroke Patients. | |
| | |
MedLine Citation:
|
PMID: 21346341 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background and Purpose: We aimed to validate the usefulness of the Essen Stroke Risk Score (ESRS) to predict stroke recurrence in a hospital-based follow-up study. Methods: We followed up 730 consecutive patients admitted to a neurological stroke unit in Berlin, Germany, with ischemic stroke (IS) or transient ischemic attack (TIA). The mean follow-up time was 13.4 months (SD 5.9). We calculated the time of event-free survival by Kaplan-Meier estimates. Results: The cumulative rate of a recurrent stroke was 10.4% (76 of 730). The risk of a recurrent stroke was significantly higher in patients with an ESRS >2 (p = 0.01; log rank). The area under the curve (AUC) was 0.59. The risk of a vascular event (VE), defined as a fatal or nonfatal IS or myocardial infarction, was significantly higher in patients with an ESRS >2 (p = 0.003; log rank). The AUC was 0.58. Stratifying the data at exact 1-year follow-up, 9 of 185 (10.3%) patients with an ESRS ≤2 suffered a recurrent stroke, while 56 of 311 (18%) patients with an ESRS >2 did so (p < 0.02; χ(2)). Thirty-six of 196 (18.4%) patients with an ESRS ≤2 suffered a VE, while 156 of 353 (35.7%) patients with an ESRS >2 did so (p < 0.001; χ(2)). Conclusions: The ESRS identifies groups of patients with TIA or IS who are at significantly increased risk for a recurrent stroke and cardiovascular event. Patients with a high ESRS require short-term follow-up and reevaluation of secondary prevention strategies. |
| | |
Authors:
|
Sabine Fitzek; Lutz Leistritz; Otto W Witte; Peter U Heuschmann; Clemens Fitzek |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-2-22 |
Journal Detail:
|
Title: Cerebrovascular diseases (Basel, Switzerland) Volume: 31 ISSN: 1421-9786 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-2-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9100851 Medline TA: Cerebrovasc Dis Country: - |
Other Details:
|
Languages: ENG Pagination: 400-407 Citation Subset: - |
Copyright Information:
|
Copyright © 2011 S. Karger AG, Basel. |
Affiliation:
|
Department of Neurology, DRK-Kliniken Berlin-Köpenick, Berlin, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Stroke Aphasia: 1,500 Consecutive Cases.
Next Document: Fully automated postprocessing carries a risk of substantial overestimation of perfusion deficits in...