| Esophageal small cell carcinoma with synchronous renal cell carcinoma: a case report with review of the literature. | |
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MedLine Citation:
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PMID: 21552445 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Synchronous malignancies with an esophageal malignancy are not uncommon. However synchronous esophageal and renal cell carcinoma (RCC) is rare with only 11 cases reported in the world literature, the esophageal malignancies being adenocarcinomas or squamous cell carcinomas. Here, we report the first case of synchronous small cell carcinoma (SCC) of the esophagus with a RCC. SCC of the esophagus is an aggressive malignancy with poor prognosis constituting 0.8-2.4% of all esophageal malignancies, currently treated with induction chemotherapy followed by chemoradiotherapy. Our patient underwent chemoradiotherapy for the SCC of the esophagus followed by radical nephrectomy for the RCC. He developed metastatic disease and died 8 months after diagnosis. Larger case series are required to develop a treatment algorithm for such a rare presentation. The key points of this report are: (1) Synchronous RCC with a primary esophageal carcinoma is a rare presentation. (2) This is the first described case report of a SCC of the esophagus with a synchronous RCC. (3) Overall prognosis in a synchronous presentation is determined by the primary esophageal malignancy. (4) Esophageal carcinomas with synchronous malignancies have a poorer prognosis compared to isolated esophageal carcinoma. |
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Authors:
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Parakkal Deepak; Radha Devi; Harikrishnan Pillai |
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Publication Detail:
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Type: Journal Article Date: 2011-04-13 |
Journal Detail:
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Title: Case reports in gastroenterology Volume: 5 ISSN: 1662-0631 ISO Abbreviation: Case Rep Gastroenterol Publication Date: 2011 |
Date Detail:
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Created Date: 2011-05-09 Completed Date: 2011-07-14 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 101474819 Medline TA: Case Rep Gastroenterol Country: Switzerland |
Other Details:
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Languages: eng Pagination: 196-200 Citation Subset: - |
Affiliation:
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University of Chicago (North Shore University Health System), Evanston, Ill., USA. |
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