Document Detail


Esophageal motility in nonacid reflux compared with acid reflux.
MedLine Citation:
PMID:  19051027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Esophageal motility has been well studied in gastroesophageal reflux disease (GERD) and acid reflux, but not in nonacid reflux. Consecutive patients who had both 24-h multichannel intraluminal impedance-pH (MII-pH) and esophageal motility tests for suspected GERD were studied. Patients were grouped into nonacid refluxers, acid refluxers, and nonrefluxers based on positive symptom correlation and objective findings of acid reflux. Of 96 patients enrolled, 21 patients (22%) were nonacid refluxers, 44 patients (46%) were acid refluxers, and 31 patients (32%) had no objective evidence of reflux. Normal motility was recorded in 86% of nonacid refluxers, 71% of acid refluxers, and 60% of nonrefluxers. Ineffective esophageal motility was seen in 24% of acid refluxers, and 5% of nonacid refluxers (P = 0.11). Symptomatic nonacid reflux events comprised 22% of patients studied for GERD symptoms by MII-pH. Esophageal motility in nonacid reflux is normal 86% of the time.
Authors:
Victor S Wang; Natan Feldman; Rie Maurer; Robert Burakoff
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Publication Detail:
Type:  Journal Article     Date:  2008-12-03
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  54     ISSN:  1573-2568     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-07-27     Completed Date:  2009-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1926-32     Citation Subset:  AIM; IM    
Affiliation:
Division of Gastroenterology and Hepatology, Brigham and Women's Hospital, Boston 02115, MA, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Case-Control Studies
Esophageal pH Monitoring
Esophagitis, Peptic / physiopathology
Esophagus / physiopathology*
Female
Gastroesophageal Reflux / physiopathology*
Gastrointestinal Motility*
Humans
Male
Middle Aged
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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