| Esophageal lichen planus: the Mayo Clinic experience. | |
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MedLine Citation:
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PMID: 10770369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lichen planus (LP) is an inflammatory papulosquamous disease which may affect the squamous epithelium of the esophagus. We reviewed six patients with esophageal lichen planus (ELP) seen at Mayo Clinic Rochester between 1984 and 1998. The presenting symptoms were dysphagia (in all six patients) and odynophagia (two patients). Cervical esophageal strictures were seen in four patients; average number of esophageal dilatations required was 15 (range, 10-18). Esophageal biopsies demonstrated the classical histologic findings of ELP in two patients, and a lymphocytic infiltrate in the other four. Concomitant lichen planus (LP) was seen at other sites in five patients: all five had oral LP preceeded by ELP symptoms in all five; three had genital LP preceeded by ELP symptoms in all three; two had dermal LP, preceeded by ELP symptoms in one. Proton pump inhibitors were tried unsuccessfully in all patients. Four patients were started on systemic steroid medication; three had resolution of symptoms within 1 month. |
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Authors:
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G C Harewood; J A Murray; A J Cameron |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E Volume: 12 ISSN: 1120-8694 ISO Abbreviation: Dis. Esophagus Publication Date: 1999 |
Date Detail:
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Created Date: 2000-05-17 Completed Date: 2000-05-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8809160 Medline TA: Dis Esophagus Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 309-11 Citation Subset: IM |
Affiliation:
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Dept of Gastroenterology, Mayo Clinic Rochester, MN 55905, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Biopsy, Needle Esophageal Diseases / diagnosis*, drug therapy*, pathology Esophagoscopy Female Glucocorticoids / administration & dosage* Hospitals, University Humans Lichen Planus / diagnosis*, drug therapy*, pathology Middle Aged Minnesota Prednisone / administration & dosage* Prognosis Retrospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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