| Esophageal involvement as an initial manifestation of Churg-Strauss syndrome. | |
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MedLine Citation:
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PMID: 17261449 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Churg-Strauss syndrome (CSS) is a systemic disease characterized by asthma, blood and tissue eosinophilia, and necrotizing vasculitis with extravascular eosinophilic granulomas. CASES: We describe two cases of patients with CSS: a 56-year-old man, whose presentation was highly unusual because its initial predominant manifestation was odynophagia, and a 35-year-old man whose disease was diagnosed after a work-up because of nausea, vomiting and abdominal pain. In both cases, thoracic computerized tomography scans showed congestive esophagitis with a markedly thickened esophageal wall at diagnosis and at relapse. Both the vasculitis and the esophageal involvement improved with treatment. DISCUSSION: Gastrointestinal (GI) involvement is frequent in CSS patients and is one of the major causes of death associated with CSS. Nonetheless, eosinophilic vasculitis-related esophagitis is very rare. |
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Authors:
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Olivier Mir; Eve-Marie Nazal; Pascal Cohen; Olivier Vignaux; Alain Krivitzky; Boyan Christoforov; Raymond Jian; Luc Mouthon; Loïc Guillevin |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2006-12-13 |
Journal Detail:
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Title: Presse médicale (Paris, France : 1983) Volume: 36 ISSN: 0755-4982 ISO Abbreviation: Presse Med Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-01-30 Completed Date: 2007-03-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8302490 Medline TA: Presse Med Country: France |
Other Details:
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Languages: eng Pagination: 57-60 Citation Subset: IM |
Affiliation:
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Service de Médecine Interne, Centre de Référence Maladies Rares, Hôpital Cochin, AP-HP, Université Paris Descartes, Paris. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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etiology Adult Churg-Strauss Syndrome / diagnosis* Deglutition Disorders / etiology Esophagitis / etiology* Humans Male Middle Aged Nausea / etiology Vomiting / etiology |
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