Document Detail


Esophageal exfoliative cytology samplers. A comparison of three types.
MedLine Citation:
PMID:  11015982     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare three types of esophageal exfoliative cytology samplers in terms of patient acceptability, ease of use, final destination of the sampler tip in the gastrointestinal tract and cellular yield. STUDY DESIGN: A controlled, single-blind, cross-over study was undertaken to compare the balloon, sponge and sponge-mesh samplers in healthy volunteers. After completing the three procedures in random order, participants were asked about their preferred method. Ease of use was defined as the technician's ability to perform the intubation successfully. Final destination of the samplers was assessed fluoroscopically. Cytopathologists determined the cellular yield of each sampler using the Bethesda System. RESULTS: Sixty-two volunteers participated. The two encapsulated samplers were significantly preferred over the balloon (P < .0001). There was no significant difference in ease of use, final destination or cellular yield of the three techniques. All three samplers were successfully intubated on the first attempt and retrieved adequate numbers of squamous and glandular cells in > 78% of cases. CONCLUSION: All three samplers obtained satisfactory yields of squamous and glandular cells, but the encapsulated samplers were more patient acceptable. The sponge-mesh sampler may be the least complicated sampler for field screening use. Larger-scale studies will be required to test the accuracy of these three samplers for detecting esophageal dysplasia and carcinoma.
Authors:
A Sepehr; P Razavi; F Saidi; P Salehian; M Rahmani; A Shamshiri
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta cytologica     Volume:  44     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    2000 Sep-Oct
Date Detail:
Created Date:  2000-10-18     Completed Date:  2000-10-18     Revised Date:  2010-04-12    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  797-804     Citation Subset:  IM    
Affiliation:
Modarress General Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. sepehr@iarc.fr
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MeSH Terms
Descriptor/Qualifier:
Biopsy / instrumentation*,  methods
Esophageal Neoplasms / prevention & control*
Esophagus / pathology*
Humans
Mass Screening / instrumentation*,  methods*
Predictive Value of Tests
Single-Blind Method

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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