Document Detail


Esophageal Small-cell Carcinoma with Syndrome of Inappropriate Secretion of Antidiuretic Hormone.
MedLine Citation:
PMID:  21576835     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Small-cell carcinoma (SCC) of the esophagus is rare, and its clinical characteristics remain poorly understood. A 54-year-old man was given a diagnosis of esophageal SCC and underwent esophagectomy. Four months after surgery, he was admitted to our hospital because of rapidly developing hyponatremia. Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH) due to extensive recurrence of SCC was diagnosed. Combined chemotherapy with irinotecan and cisplatin has dramatically reduced metastatic tumors, and it was concomitantly effective for SIADH. This case demonstrates that esophageal SCC could induce SIADH as a paraneoplastic syndrome and that the above combined chemotherapy was feasible and effective.
Authors:
Takayuki Ando; Ayumu Hosokawa; Hidemoto Yamawaki; Yuushi Hasumoto; Shinya Kajiura; Yuko Itaya; Akira Ueda; Nobuhiro Suzuki; Jun Nishikawa; Haruka Fujinami; Takako Miyazaki; Kouhei Ogawa; Toshiro Sugiyama
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Publication Detail:
Type:  Journal Article     Date:  2011-05-01
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  50     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2011  
Date Detail:
Created Date:  2011-05-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1099-103     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan.
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