Document Detail


Escherichia coli O157:H7 and its significance in foods.
MedLine Citation:
PMID:  1854598     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Escherichia coli O157:H7 was conclusively identified as a pathogen in 1982 following its association with two food-related outbreaks of an unusual gastrointestinal illness. The organism is now recognized as an important cause of foodborne disease, with outbreaks reported in the U.S.A., Canada, and the United Kingdom. Illness is generally quite severe, and can include three different syndromes, i.e., hemorrhagic colitis, hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. Most outbreaks have been associated with eating undercooked ground beef or, less frequently, drinking raw milk. Surveys of retail raw meats and poultry revealed E. coli O157:H7 in 1.5 to 3.5% of ground beef, pork, poultry, and lamb. Dairy cattle, especially young animals, have been identified as a reservoir. The organism is typical of most E. coli, but does possess distinguishing characteristics. For example, E. coli O157:H7 does not ferment sorbitol within 24 h, does not possess beta-glucuronidase activity, and does not grow well or at all at 44-45.5 degrees C. The organism has no unusual heat resistance; heating ground beef sufficiently to kill typical strains of salmonellae will also kill E. coli O157:H7. The mechanism of pathogenicity has not been fully elucidated, but clinical isolates produce one or more verotoxins which are believed to be important virulence factors. Little is known about the significance of pre-formed verotoxins in foods. The use of proper hygienic practices in handling foods of animal origin and proper heating of such foods before consumption are important control measures for the prevention of E. coli O157:H7 infections.
Authors:
M P Doyle
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of food microbiology     Volume:  12     ISSN:  0168-1605     ISO Abbreviation:  Int. J. Food Microbiol.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-08-23     Completed Date:  1991-08-23     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8412849     Medline TA:  Int J Food Microbiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  289-301     Citation Subset:  IM    
Affiliation:
Department of Food Microbiology and Toxicology, University of Wisconsin, Madison.
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MeSH Terms
Descriptor/Qualifier:
Animals
Disease Outbreaks*
Escherichia coli / growth & development,  pathogenicity*
Escherichia coli Infections / microbiology*
Food Microbiology*
Foodborne Diseases / microbiology*
Humans
Meat

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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