| Escaping the correction for body surface area when calculating glomerular filtration rate in children. | |
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MedLine Citation:
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PMID: 18481062 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: (51)Cr ethylene diamine tetraacetic acid ((51)Cr EDTA) clearance is nowadays considered as an accurate and reproducible method for measuring glomerular filtration rate (GFR) in children. Normal values in function of age, corrected for body surface area, have been recently updated. However, much criticism has been expressed about the validity of body surface area correction. The aim of the present paper was to present the normal GFR values, not corrected for body surface area, with the associated percentile curves. METHODS: For that purpose, the same patients as in the previous paper were selected, namely those with no recent urinary tract infection, having a normal left to right (99m)Tc MAG3 uptake ratio and a normal kidney morphology on the early parenchymal images. A single blood sample method was used for (51)Cr EDTA clearance measurement. RESULTS: Clearance values, not corrected for body surface area, increased progressively up to the adolescence. CONCLUSION: The percentile curves were determined and allow, for a single patient, to estimate accurately the level of non-corrected clearance and the evolution with time, whatever the age. |
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Authors:
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Amy Piepsz; Marianne Tondeur; Hamphrey Ham |
Publication Detail:
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Type: Journal Article Date: 2008-05-15 |
Journal Detail:
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Title: European journal of nuclear medicine and molecular imaging Volume: 35 ISSN: 1619-7070 ISO Abbreviation: Eur. J. Nucl. Med. Mol. Imaging Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-22 Completed Date: 2008-12-19 Revised Date: 2009-03-18 |
Medline Journal Info:
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Nlm Unique ID: 101140988 Medline TA: Eur J Nucl Med Mol Imaging Country: Germany |
Other Details:
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Languages: eng Pagination: 1669-72 Citation Subset: IM |
Affiliation:
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Department of Radioisotopes, CHU St Pierre, Brussels, Belgium. amypiepsz@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Body Surface Area* Calibration Child Child, Preschool Glomerular Filtration Rate* Humans Infant Infant, Newborn Sensitivity and Specificity |
| Comments/Corrections | |
Erratum In:
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Eur J Nucl Med Mol Imaging. 2009 Feb;36(2):332-3 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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