Document Detail


Erythropoietin in premature infants.
MedLine Citation:
PMID:  6182736     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The regulation of erythropoiesis during the first three months of life was studied in 30 premature infants who had haemoglobin concentrations which were lower than in term in fants of the same postdelivery age. Erythropoietin and erythropoiesis inhibitors were measured by means of an exhypoxic polycythaemic mouse bioassay. The percentage of haemoglobin F was determined as well. An increased erythropoietin level was detected only in six infants older than six weeks, whose blood haemoglobin concentration was lower than 100 g/l, while in serum from other babies erythropoietin was undetectable by the method used. Erythropoiesis inhibitors were present in 80% of the samples tested. The results presented indicate that in premature infants erythropoiesis is regulated through erythropoietin and that inhibitors of erythropoiesis take part in this regulation as well, but that the haemoglobin level at which erythropoietin is increased is lower in preterm infants than in term babies.
Authors:
L Biljanović-Paunović; V Pavlović-Kentera; R Nikolić; P Kićevac
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  71     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Assay
Erythropoiesis*
Erythropoietin / blood*,  urine
Fetal Hemoglobin / analysis
Hemoglobins / analysis
Humans
Infant
Infant, Newborn
Infant, Premature*
Mice
Chemical
Reg. No./Substance:
0/Hemoglobins; 11096-26-7/Erythropoietin; 9034-63-3/Fetal Hemoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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