Document Detail

Erythropoiesis and performance after two weeks of living high and training low in well trained triathletes.
MedLine Citation:
PMID:  12439771     Owner:  NLM     Status:  MEDLINE    
The purpose of our study was to evaluate hematologic acclimatization during 2 weeks of intensive normoxic training with regeneration at moderate altitude (living high-training low, LHTL) and its effects on sea-level performance in well trained athletes compared to another group of equally trained athletes under control conditions (living low - training low, CONTROL). Twenty-one triathletes were ascribed either to LHTL (n = 11; age: 23.0 +/- 4.3 yrs; VO 2 max: 62.5 +/- 9.7 [ml x min -1 x kg -1]) living at 1956 m of altitude or to CONTROL (n = 10; age: 18.7 +/- 5.6 yrs; VO 2 max: 60.5 +/- 6.7 ml x min -1 x kg -1) living at 800 m. Both groups performed an equal training schedule at 800 m. VO 2 max, endurance performance, erythropoietin in serum, hemoglobin mass (Hb tot, CO-rebreathing method) and hematological quantities were measured. A tendency to improved performance in LHTL after the camp was not significant (p < 0.07). Erythropoietin concentration increased temporarily in LHTL (Delta 14.3 +/- 8.7 mU x ml -1; p < 0.012). Hb tot remained unchanged in LHTL whereas was slightly decreased from 12.5 +/- 1.3 to 11.9 +/- 1.3g x kg -1 in CONTROL (p < 0.01). As the reticulocyte number tended to higher values in LHTL than in CONTROL, it seems that a moderate stimulation of erythropoiesis during regeneration at altitude served as a compensation for an exercise-induced destruction of red cells.
C Dehnert; M Hütler; Y Liu; E Menold; C Netzer; R Schick; B Kubanek; M Lehmann; D Böning; J M Steinacker
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of sports medicine     Volume:  23     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-11-19     Completed Date:  2003-03-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  561-6     Citation Subset:  IM    
Dept. of Sports and Rehabilitation Medicine, Medical Centre, University of Ulm, Germany.
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MeSH Terms
Acclimatization / physiology*
Erythropoiesis / physiology*
Exercise / physiology*
Oxygen Consumption / physiology
Physical Education and Training / methods*
Sports / physiology*
Task Performance and Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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