Document Detail

Erythrocyte metabolism.
MedLine Citation:
PMID:  799310     Owner:  NLM     Status:  MEDLINE    
In summary, red cell carbohydrate metabolism plays an important role in the cell, both for maintaining cell viability through ATP and for maintaining proper oxygen release through DPG. These functions are compromised by traditional liquid storage. Frozen storage maintains these functions for an indefinite period of time. However, the cells are not metabolically perfect, at least with current techniques, and assay of glycolytic intermediates is a useful monitoring device to evaluate the effects of various manipulations, particularly after thawing and washing have taken place.
G J Brewer; W C Kruckeberg; C J Westover; H A Oberman
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Progress in clinical and biological research     Volume:  11     ISSN:  0361-7742     ISO Abbreviation:  Prog. Clin. Biol. Res.     Publication Date:  1976  
Date Detail:
Created Date:  1977-05-27     Completed Date:  1977-05-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7605701     Medline TA:  Prog Clin Biol Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  5-19     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenosine Triphosphate / blood
Blood Preservation
Carbohydrates / blood*
Diphosphoglyceric Acids / blood
Erythrocytes / metabolism*
Purines / blood
Time Factors
Reg. No./Substance:
0/Carbohydrates; 0/Diphosphoglyceric Acids; 0/Purines; 56-65-5/Adenosine Triphosphate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Transfusion of frozen-washed red cells in preventing hepatitis.
Next Document:  Cryobiology overview of red cell preservation: achievements and prospective.