Document Detail

Erythrocyte deformability in workers exposed to lead.
MedLine Citation:
PMID:  1792066     Owner:  NLM     Status:  MEDLINE    
Erythrocyte deformability and other hematological indicators were determined in 17 male workers exposed to lead at a secondary lead refinery and 13 controls. Blood lead, urine lead, urine coproporphyrin, delta-aminolevulinic acid and erythrocyte zinc protoporphyrin were determined to evaluate the degree of lead exposure in the lead workers above. For the measurement of erythrocyte deformability, the microfilter method was used. The results were summarized as follows: 1. The mean values of blood lead, urine lead, urine coproporphyrin, urine delta-aminolevulinic acid and erythrocyte zinc protoporphyrin levels in lead workers were 53.5 micrograms/100g, 141.4 micrograms/l, 115.9 micrograms/l, 12.0 mg/l and 68.9 micrograms/dl respectively, suggesting a moderate influence of lead exposure. 2. The mean values of erythrocyte count, hematocrit and hemoglobin were significantly lower in lead workers than those in controls. No significant differences were found in the mean values of mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and corpuscular natrium and potassium between lead workers and controls. 3. Erythrocyte deformability was significantly reduced in lead workers compared with controls.
S Horiguchi; S Matsumura; K Fukumoto; I Karai; G Endo; K Teramoto; K Shinagawa; I Kiyota; F Wakitani; S Takise
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Osaka city medical journal     Volume:  37     ISSN:  0030-6096     ISO Abbreviation:  Osaka City Med J     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-04-02     Completed Date:  1992-04-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376413     Medline TA:  Osaka City Med J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  149-55     Citation Subset:  IM    
Department of Preventive Medicine and Environmental Health, Osaka City University Medical School, Japan.
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MeSH Terms
Erythrocyte Deformability / drug effects*
Lead / adverse effects*,  blood
Lead Poisoning / blood*
Middle Aged
Occupational Diseases / blood*
Reg. No./Substance:

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