| Erythrocyte autoantibodies, autoimmune haemolysis and pregnancy. | |
| | |
MedLine Citation:
|
PMID: 6814064 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The clinical and serological records of 20 pregnant patients with erythrocyte autoantibodies were critically reviewed and analysed. This series, the largest reported, confirmed an association between erythrocyte autosensitization and pregnancy, and suggested that this occurred on an average of 1 in 50,000 pregnancies. The clinical presentation varied from severe haemolytic anaemia to serological abnormalities discovered during the routine testing of well patients; overt haemolysis was present in 7 cases. Treatment was only necessary in 3 patients where the haemolysis was severe. 3 infants were mildly affected with haemolytic disease due to the maternal autoantibodies crossing the placenta but no treatment was needed. The risks to the infant were increased when other active autoimmune conditions (e.g., systemic lupus erythematosus) were present. With early diagnosis and appropriate treatment, outlook for mother and child is good. |
| | |
Authors:
|
R J Sokol; S Hewitt; B K Stamps |
Related Documents
:
|
11422194 - Pregnancy induces nonimmunoglobulin insulin-binding activity in both maternal and cord ... 2111454 - Structural and functional similarities of breadfruit seed lectin and jacalin. 10426674 - Pregnancy complications in women with recurrent miscarriage associated with antiphospho... 960074 - Some parameters of lymphocyte antibody activity through pregnancy and further eluates o... 3889164 - A monoclonal antibody based solid-phase enzyme-binding assay to measure levels of place... 16364334 - Chemometric treatment of vanillin fingerprint chromatograms. effect of different signal... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Vox sanguinis Volume: 43 ISSN: 0042-9007 ISO Abbreviation: Vox Sang. Publication Date: 1982 |
Date Detail:
|
Created Date: 1982-12-21 Completed Date: 1982-12-21 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0413606 Medline TA: Vox Sang Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 169-76 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
ABO Blood-Group System
/
immunology* Adult Anemia, Hemolytic, Autoimmune / diagnosis, etiology* Autoantibodies / biosynthesis* Blood Group Incompatibility / diagnosis Coombs' Test England Female Humans Infant, Newborn Pregnancy Pregnancy Complications, Hematologic / diagnosis, etiology, immunology* Rh-Hr Blood-Group System / immunology* |
| Chemical | |
Reg. No./Substance:
|
0/ABO Blood-Group System; 0/Autoantibodies; 0/Rh-Hr Blood-Group System |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dynamics of weight gain in calves fed with microalgae
Next Document: The costs and risks of medical care: an annotated bibliography for clinicians and educators.