| Erythrina alkaloids and a pterocarpan from the bark of Erythrina subumbrans. | |
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MedLine Citation:
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PMID: 18171023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three new erythrina alkaloids, (+)-10,11-dioxoerythratine (1), (+)-10,11-dioxoepierythratidine (2), and (+)-10,11-dioxoerythratidinone (3), and a new pterocarpan, 1-methoxyerythrabyssin II (4), were isolated from the bark of Erythrina subumbrans, together with seven known pterocarpans, erythrabyssin II, erybraedin A, erystagallin A, erycristagallin, erythrabissin-1, eryvarin A, and hydroxycristacarpone, three flavanones, 5-hydroxysophoranone, abyssinone V, and lespedezaflavanone B, three triterpenes, sophoradiol, soyasapogenol B, and lupeol, and one isoflavanone, vogelin C. Their structures were elucidated on the basis of spectroscopic data. Some isolates were tested for antiplasmodial, antimycobacterial, and cytotoxic activities. |
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Authors:
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Thitima Rukachaisirikul; Phongsak Innok; Apichart Suksamrarn |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-01-03 |
Journal Detail:
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Title: Journal of natural products Volume: 71 ISSN: 0163-3864 ISO Abbreviation: J. Nat. Prod. Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-01-25 Completed Date: 2008-04-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7906882 Medline TA: J Nat Prod Country: United States |
Other Details:
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Languages: eng Pagination: 156-8 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand. thitima@ru.ac.th |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alkaloids
/
chemistry,
isolation & purification*,
pharmacology Animals Antimalarials / chemistry, isolation & purification*, pharmacology Antineoplastic Agents, Phytogenic / chemistry, isolation & purification*, pharmacology Antitubercular Agents / chemistry, isolation & purification*, pharmacology Drug Screening Assays, Antitumor Erythrina / chemistry* Female Humans Inhibitory Concentration 50 Microbial Sensitivity Tests Mycobacterium tuberculosis / drug effects Plant Bark / chemistry Plants, Medicinal / chemistry* Plasmodium falciparum / drug effects Pterocarpans / chemistry, isolation & purification*, pharmacology Thailand |
| Chemical | |
Reg. No./Substance:
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0/1-methoxyerythrabyssin II; 0/10,11-dioxoepierythratidine; 0/10,11-dioxoerythratidinone; 0/10,11-dioxoerythratine; 0/Alkaloids; 0/Antimalarials; 0/Antineoplastic Agents, Phytogenic; 0/Antitubercular Agents; 0/Pterocarpans |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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