Document Detail

Erythema nodosum: the underlying conditions.
MedLine Citation:
PMID:  10870657     Owner:  NLM     Status:  MEDLINE    
Erythema nodosum (EN) is a cutaneous reaction consisting of inflammatory, tender nodular lesions and is associated with a wide variety of disease processes. The aim of our study was to investigate the frequency of different aetiologies of EN. One hundred and thirty-two EN patients were investigated in a prospective study during the period 1984-1990. The evaluation of all patients began with a medical and family history and completed with a thorough physical examination and detailed laboratory and immunological work-up. In addition, various diagnostic procedures were performed where and when indicated. One hundred and ten patients (83%) were women. Their mean age was 41.0+/-14.0 years, range 18-79 years. In 35% the cause of EN was not found. Sarcoidosis was revealed in 28% of the patients, infections in 17.3% and tuberculosis in 1.5%. Other aetiologic factors were Adamantiadis-Behçet's syndrome (3.8%), pregnancy (6%), oral contraceptives (3.8%) and other drugs (3.8%). The aetiology of EN was not found in 35% of the patients. Sarcoidosis and infections were frequent causes of EN, whereas autoimmune rheumatic diseases rarely cause EN.
D N Psychos; P V Voulgari; F N Skopouli; A A Drosos; H M Moutsopoulos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical rheumatology     Volume:  19     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2000  
Date Detail:
Created Date:  2000-09-25     Completed Date:  2000-11-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  212-6     Citation Subset:  IM    
Department of Internal Medicine, Medical School, University of Ioannina, Greece.
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MeSH Terms
Erythema Nodosum / etiology*,  pathology,  physiopathology
Infection / complications,  epidemiology
Middle Aged
Prospective Studies
Sarcoidosis / complications,  epidemiology
Tuberculosis / complications,  epidemiology

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