Document Detail

Erythema nodosum caused by omeprazole.
MedLine Citation:
PMID:  8804848     Owner:  NLM     Status:  MEDLINE    
We report a case of erythema nodosum caused by omeprazole. This side effect of omeprazole has not been previously reported. A 35-year-old white woman developed multiple tender erythematous nodules over the anterior aspect of her upper and lower extremities, fever, malaise, and edema. Her symptoms resolved with withdrawal of all preexisting medications and conservative treatment. Her symptoms flared soon after a rechallenge with omeprazole. A thorough history, physical examination, laboratory evaluation, and roentgenogram failed to reveal another cause for erythema nodosum. It is clear from the rechallenge that this patient's erythema nodosum was caused by omeprazole. We consider that omeprazole should be added to the list of medications known to cause erythema nodosum.
R M Ricci; K C Deering
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cutis     Volume:  57     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-12-04     Completed Date:  1996-12-04     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  434     Citation Subset:  IM    
Department of Dermatology, Wilford Hall Medical Center, Lackland Air Force Base, Texas 78236-5300, USA.
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MeSH Terms
Anti-Ulcer Agents / adverse effects*
Drug Eruptions / etiology*,  pathology
Edema / chemically induced
Erythema Nodosum / chemically induced*,  pathology
Leg Dermatoses / chemically induced,  pathology
Medical History Taking
Omeprazole / adverse effects*
Physical Examination
Reg. No./Substance:
0/Anti-Ulcer Agents; 73590-58-6/Omeprazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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