| Erythema multiforme and Stevens-Johnson syndrome. Descriptive and therapeutic controversy. | |
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MedLine Citation:
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PMID: 2198136 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diagnosis and particularly the management of erythema multiforme and Stevens-Johnson syndrome are controversial in medical textbooks and thus in individual cases. In these diseases, fatalities may result from various causes, including secondary infection or visceral organ damage to lung, liver, or kidneys. We present a series of 13 cases managed by one group of physicians which demonstrates the controversy in certain cases, and we review the controversy in the medical literature. Corticosteroid therapy used in this series was considered beneficial in every case by the managing physician and lifesaving in some cases. There were no fatalities in this series. Although the summation may be considered as our opinion only, the frequently suggested "controlled trial of corticosteroid therapy" can probably never be done for ethical reasons, and series such as this will have to establish the standard of therapy. |
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Authors:
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R Patterson; M S Dykewicz; A Gonzalzles; L C Grammer; D Green; P A Greenberger; K G McGrath; C L Walker |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Chest Volume: 98 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1990 Aug |
Date Detail:
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Created Date: 1990-09-04 Completed Date: 1990-09-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 331-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Northwestern University Medical School, Chicago. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Epidermal Necrolysis, Toxic Erythema Multiforme* / diagnosis, drug therapy Female Humans Hydrocortisone / therapeutic use Middle Aged Prednisone / therapeutic use Stevens-Johnson Syndrome* / diagnosis, drug therapy Terminology as Topic* |
| Grant Support | |
ID/Acronym/Agency:
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AI 11403/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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