Document Detail

Ervatamia coronaria: chemical constituents and some pharmacological activities.
MedLine Citation:
PMID:  8778503     Owner:  NLM     Status:  MEDLINE    
A new bisindole alkaloid, 19,20-dihydroervahanine A was isolated from the stems of Ervatamia coronaria grown in Brazil, together with five known alkaloids: coronaridine, heyneanine, voacristine, voacamine, descarbomethoxyvoacamine and five phenolic acids: vanillic, gentisic, syringic, 4-hydroxybenzoic and salicylic acid. The aqueous and alcoholic extracts, when administered p.o. or i.p. to rats 1 h before subplantar injection of carrageenin had a significant anti-inflammatory effect. The alcoholic extract also had an analgesic effect and increased the pentobarbital induced sleeping time.
A T Henriques; A A Melo; P R Moreno; L L Ene; J A Henriques; E E Schapoval
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of ethnopharmacology     Volume:  50     ISSN:  0378-8741     ISO Abbreviation:  J Ethnopharmacol     Publication Date:  1996 Jan 
Date Detail:
Created Date:  1996-09-17     Completed Date:  1996-09-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7903310     Medline TA:  J Ethnopharmacol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  19-25     Citation Subset:  IM    
Faculty of Pharmacy, UFRGS, Porto Alegre, RS, Brazil.
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MeSH Terms
Alkaloids / analysis,  pharmacology
Analgesics / pharmacology
Anti-Inflammatory Agents / pharmacology
Indoles / analysis,  pharmacology
Plant Extracts / pharmacology
Plants, Medicinal / chemistry*
Rats, Wistar
Sleep / drug effects
Reg. No./Substance:
0/Alkaloids; 0/Analgesics; 0/Anti-Inflammatory Agents; 0/Indoles; 0/Plant Extracts

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