| Eruptive xanthomas and chest pain in the absence of coronary artery disease. | |
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MedLine Citation:
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PMID: 11324391 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Because hyperlipidemia may present as xanthomas, a dermatologist may be the first to diagnose these skin lesions and associated lipid abnormalities. Xanthomas are of concern because of their association with coronary artery disease and pancreatitis. We describe the case of a 40-year-old white male with chest pain and eruptive xanthomas. Laboratory tests revealed severe hypercholesterolemia, hypertriglyceridemia, and diabetes mellitus, and the histopathology of the skin lesions was consistent with eruptive xanthomas. Surprisingly, even with overwhelming risk factors for both atherosclerosis and pancreatitis, this patient did not show evidence of either disease process. After initiating therapy for the diabetes and hyperlipidemia, the patient has had no recurrence of chest pain, and the skin lesions have gradually resolved. The most likely explanation for this patient's pattern of symptoms and laboratory results is the chylomicronemia syndrome, which can be seen in patients with type I or type V hyperlipoproteinemia. |
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Authors:
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P P Hentges; C J Huerter |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cutis; cutaneous medicine for the practitioner Volume: 67 ISSN: 0011-4162 ISO Abbreviation: Cutis Publication Date: 2001 Apr |
Date Detail:
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Created Date: 2001-04-27 Completed Date: 2001-09-06 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0006440 Medline TA: Cutis Country: United States |
Other Details:
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Languages: eng Pagination: 299-302 Citation Subset: IM |
Affiliation:
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Creighton University School of Medicine, Omaha, Nebraska, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chest Pain / complications* Chylomicrons / blood Diabetes Complications Diabetes Mellitus / drug therapy Humans Hypercholesterolemia / complications, drug therapy Hypertriglyceridemia / complications, drug therapy Male Skin / pathology Xanthomatosis / complications*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Chylomicrons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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