Document Detail


Eruptive tumors of the follicular infundibulum presenting as hypopigmented macules on the buttocks of two Black African males.
MedLine Citation:
PMID:  22443395     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We report two cases of eruptive tumors of the follicular infundibulum (TFI) with an unusual clinical presentation which has not been described previously in literature. In both cases, the appearance was strikingly similar, consisting of multiple asymptomatic hypopigmented macules on the buttocks of two Black African males, aged 38 and 55 years old. In both cases, the eruption had evolved over several months. The individual lesions were of similar size, approximately 1 cm, with irregular and ill-defined borders. Histopathological examination revealed a superficial and horizontal plate-like proliferation of keratinocytes emanating from the epidermis with multiple slender attachments. Pale keratinocytes were present within the epithelial plates. A Fontana stain showed a loss of melanin pigment from the epithelial plates. Orcein (elastic) stain highlighted an increase of the number of the elastic fibers surrounding the tumor. On the basis of these findings, a diagnosis of eruptive TFI was established for both cases. Among the various presentations of TFI, only the eruptive variant appears to be clinically distinctive, with asymptomatic hypopigmented macules usually located on the face, neck and upper trunk. Eruptive TFI should also be added to the clinical differential diagnosis of multiple hypopigmented macules on the buttocks of Black patients. Kolivras A, Moulonguet I, Ruben BS, Sass U, Cappelletti L, André J. Eruptive tumors of the follicular infundibulum presenting as hypopigmented macules on the buttocks of two Black African males.
Authors:
Athanassios Kolivras; Isabelle Moulonguet; Beth S Ruben; Ursula Sass; Letizia Cappelletti; Josette André
Related Documents :
22428755 - Three new cycloartane glycosides from nervilia fordii.
22897855 - Gene-targeting of phd2 improves tumor response to chemotherapy and prevents side-toxicity.
16061675 - Therapeutic epha2 gene targeting in vivo using neutral liposomal small interfering rna ...
22406375 - Chromosomal imbalances in primary hepatic carcinosarcoma.
22854675 - Biological heterogeneity of cancer: implication to therapy.
25261355 - Identification of tumor-binding scfv derived from clonally related b cells in tumor and...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cutaneous pathology     Volume:  39     ISSN:  1600-0560     ISO Abbreviation:  J. Cutan. Pathol.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425124     Medline TA:  J Cutan Pathol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  444-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 John Wiley & Sons A/S.
Affiliation:
Department of Dermatology and Dermatopathology, Saint-Pierre Hospital, Université Libre de Bruxelles, Brussels, Belgium Private Dermatopathology practice, Paris, France Department of Dermatology, University of California, San Francisco, CA, USA Department of Pathology, University of California, San Francisco, CA, USA Department of Dermatology, Saint-Pierre Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Hereditary mucoepithelial dysplasia: unique histopathological findings in skin lesions.
Next Document:  Development of a new CARD-FISH protocol for quantification of Legionella pneumophila and its applica...