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Eruptive microvenular hemangiomas in 4 chinese patients: clinicopathologic correlation and review of the literature.
MedLine Citation:
PMID:  20881833     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Microvenular hemangioma (MVH) is an uncommon benign vascular neoplasm that usually occurs as a solitary asymptomatic red or purple papule, nodule, or plaque with a predilection for the upper extremities. Patients with more than 1 lesion, that is, multiple MVHs, are extremely rare. We describe the clinicopathologic features of 4 Chinese patients who had a rapidly progressive abrupt onset of numerous MVHs numbering in the tens to hundreds. Clinically, the correct diagnosis of MVH could not be made in any of our patients; however, histologic examination revealed the characteristic features of MVH. Immunohistochemical stains were performed in all cases and showed the vessel lining cells to be positive for CD34, CD31, and factor VIII-related antigen. Polymerase chain reaction for human herpesvirus-8 was negative in all cases. The differential diagnosis and review of the literature of patients with multiple MVHs are presented.
Authors:
Xiu-Lian Xu; Cui-Rong Xu; Hao Chen; Yuan-Hua Cao; Xue-Si Zeng; Jian-Fang Sun; Ying Guo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  32     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  837-40     Citation Subset:  IM    
Affiliation:
Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China.
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