Document Detail


Errors in the selection of dialysate concentrates cause severe metabolic acidosis during bicarbonate hemodialysis.
MedLine Citation:
PMID:  9288865     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Severe metabolic acidosis occurred during bicarbonate hemodialysis as the result of an error made in the selection of the dialysate concentrate. We questioned whether or not it was possible for the dialysis equipment to regulate the proportions in the dialysate fluid using an incorrect dialysate concentrate and still obtain the proper conductivity. We simulated this situation in vitro and found that during bicarbonate dialysis an inappropriately acidic dialysate fluid could replace the normal dialysate with an adequate range of conductivity still being maintained and therefore no triggering of alarms. The investigation showed that the dialysis machines were not adequately adjusted for sensitivity to the concentrates being employed during dialysis. We concluded that dialysis equipment should be fitted with on-line pH meters with alarm systems.
Authors:
J F Navarro; C Mora-Fernández; J Garcia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Artificial organs     Volume:  21     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1998-01-08     Completed Date:  1998-01-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  966-8     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Hospital Ntra. Señora de Candelaria, Canary Islands, de Tenerife, Spain.
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MeSH Terms
Descriptor/Qualifier:
Acidosis / blood,  etiology*
Bicarbonates / blood*
Dialysis Solutions / standards
Electric Conductivity
Humans
Hydrogen-Ion Concentration
Renal Dialysis / adverse effects*,  instrumentation
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Dialysis Solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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