| Erosion-inhibiting potential of a stannous chloride-containing fluoride solution under acid flow conditions in vitro. | |
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MedLine Citation:
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PMID: 20627197 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: This study aimed to analyse the erosion-inhibiting potential of a single application of stannous chloride-containing fluoride solution on pellicle-covered enamel and dentine under constant acid flow conditions in vitro. DESIGN: Bovine enamel (n=60) and dentine (n=60) samples were exposed 1h to the oral cavity of 4 healthy volunteers to allow for in situ pellicle formation. Pellicle-covered samples were randomly assigned to three groups (each n=20 enamel and n=20 dentine samples; 5 enamel and 5 dentine samples/volunteer) and treated once with a SnCl2/AmF/NaF (800 ppm Sn(II), 500 ppm F, pH 4.5) or a NaF solution (500 ppm F, pH 4.5) for 2 min or remained untreated (controls). Samples were eroded with hydrochloric acid (pH 2.6) in a small erosion chamber at 60 microl/min for 25 min. Calcium release into the acid was monitored in consecutive 30s intervals for 5 min, then at 1 min intervals up to a total erosion time of 25 min using the Arsenazo III procedure. Data were statistically analysed by random-effects linear models (p<0.05). RESULTS: The stannous chloride-containing fluoride solution reduced calcium loss of enamel and dentine to up to 6 min and 3.5 min, respectively. Calcium loss (% of control) amounted from 24+/-7 (30s) up to 93+/-14 (6 min) in enamel and from 38+/-13 (30s) to 87+/-15 (3.5 min) in dentine. The sodium fluoride solution was unable to reduce enamel and dentine erosion at any time point. CONCLUSION: A single application of a stannous chloride-containing fluoride solution reduced enamel and dentine erosion up to 6 min and 3.5 min of constant acid flow, respectively. |
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Authors:
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Hao Yu; Florian Just Wegehaupt; Markus Zaruba; Klaus Becker; Malgorzata Roos; Thomas Attin; Annette Wiegand |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2010-07-11 |
Journal Detail:
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Title: Archives of oral biology Volume: 55 ISSN: 1879-1506 ISO Abbreviation: Arch. Oral Biol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-11 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0116711 Medline TA: Arch Oral Biol Country: England |
Other Details:
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Languages: eng Pagination: 702-5 Citation Subset: D; IM |
Copyright Information:
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Copyright 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zurich, 8032 Zurich, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Calcium / analysis Cattle Dental Enamel / drug effects, metabolism, pathology Dental Pellicle / physiology Dentin / drug effects, metabolism, pathology Diamines / therapeutic use* Female Fluorides / therapeutic use* Fluorides, Topical / therapeutic use* Humans Hydrogen-Ion Concentration Linear Models Male Sodium Fluoride / therapeutic use Tin Compounds / therapeutic use* Tin Fluorides / therapeutic use Tooth Erosion / prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/Diamines; 0/Fluorides; 0/Fluorides, Topical; 0/Olaflur; 0/Tin Compounds; 0/Tin Fluorides; 0/amine fluoride solution; 7440-70-2/Calcium; 7681-49-4/Sodium Fluoride; 7772-99-8/stannous chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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